Sesame Summit 2026 – application open

Top 5 Venture Capital Firms in Italy

Italy, with its rich history and culture, is also a burgeoning hub for technological innovation and entrepreneurial spirit. The following five venture capital firms represent the forefront of this transformation, showcasing Italy’s commitment to fostering groundbreaking ideas and businesses.

These firms are not merely investors but catalysts of change, driving innovation across diverse sectors from technology to sustainability. By supporting ambitious startups and visionary entrepreneurs, these venture capital firms are also shaping a resilient and forward-thinking Italian economy.

We took into account the number of deals per year to create this list.

blank

LVenture Group

LVenture Group is a dynamic venture capital company that focuses on investing in early-stage startups. They are dedicated to shaping the future of entrepreneurship by supporting innovative and groundbreaking ideas. Their approach is centered on nurturing startups, enhancing capital value, transforming corporate strategies, and fostering innovation in a collaborative ecosystem. With over 130 accelerated startups, a network of 50+ advisors, and a significant investment portfolio, LVenture Group plays a pivotal role in promoting change and growth within the entrepreneurial community. They offer a unique space for innovation, organizing over 300 events annually, and have created a vibrant community of game-changers and key players in innovation.

Sector focus: Software, E-commerce, Saas, IT

Round: Early Stage Venture, Seed

Total investments: 158

Founding Year: 2013

Notable Investments: Kiwibot, Pipein, Reasoned Art, Ittinsect, olivia

blank

CDP Venture Capital

CDP Venture Capital SGR is an Italian investment firm focused on fostering the growth of the Italian venture capital ecosystem. They specialize in both direct and indirect investments, aiming to promote the development of innovative startups and companies. With a strategy that includes the creation of Acceleration Programs and Technology Transfer Hubs, CDP Venture Capital SGR plays a significant role in stimulating overall market growth. Their initiatives are geared towards enabling companies, investors, and startups to find new opportunities for growth and development, contributing to the sustainable growth of the Italian venture capital landscape.

Sector focus: Software, Health Care, Information Technology, Education, Medical

Round: Series A-B

Total investments: 136

Founding Year: 2015

Notable Investments: Tau Group, MOGU, Cents, D-Orbit, W•SENSE

blank

LIFTT

LIFTT is a venture capital firm that focuses on creating a unique synergy between business creation and investments. Their approach is not solely driven by profit, but also aims to bridge the gap between innovative ideas, local territories, and capital. With a commitment to support talent and future development in their country, LIFTT plays a crucial role in the journey from research to market. They specialize in technology transfer and deriving value from research results, emphasizing the importance of new technologies and entrepreneurship in an unpredictable society.

Sector focus: Software, Biotechnology, Health Care, Information Technology, E-Commerce Platforms

Round: Seed

Total investments: 53

Founding Year: 2019

Notable Investments: NeoPhore, ALKemist Bio, Entropica Labs, PrediSurge, INTA Systems

blank

P101

P101 is a prominent venture capital firm based in Italy, committed to supporting and partnering with teams that are focused on building impactful companies. With a philosophy of investing in people committed to positive change, P101 backs resilient, intelligent, visionary, and purposeful entrepreneurs. The firm manages a substantial portfolio and has achieved a number of successful exits, showcasing their effectiveness in nurturing startups. Their approach emphasizes early partnership with founders, aiding in the transition from idea to market success.

Sector focus: E-Commerce, Software, Internet, Retail, Mobile

Round: Early Stage Venture

Total investments: 90

Founding Year: 2013

Notable Investments: Aptus.AI, Habyt, Mama Health, AppQuality, 1000Farmacie

blank

Club Italia Investimenti 2

Club Italia Investimenti 2 (Cii2) is a Milan-based investment company specializing in Venture Capital. Founded in 2013 by a group of entrepreneurs deeply involved in innovation and investment in high-tech startups, Cii2 focuses on investing in and supporting companies with significant technological content. Their investment model includes an initial investment in a large number of very young startups, acquiring about 10% of the shares. Cii2 supports these companies in finding further investments, presenting early metrics, and validating their business models with initial customers.

Sector focus: E-Commercel, Mobile, Software, Internet,iOS

Round: Early Stage Venture, Seed

Total investments: 82

Founding Year: 2013

Notable Investments: AppQuality, Titanium Challenge, Crowdway, Mymenu, Le Cicogne

you might also like

Fundraising 5 hours ago

London-based AI laboratory Ineffable Intelligence has emerged from stealth with a $1.1 billion seed round at a $5.1 billion post-money valuation, the company confirmed on 27 April 2026. The financing is the largest seed round ever raised by a European company and one of the largest first-money-in rounds in the global history of artificial intelligence. The round was co-led by Sequoia Capital and Lightspeed Venture Partners. Participating investors included Nvidia, DST Global, Index Ventures, Google, and the UK Sovereign AI Fund, the British government’s recently established vehicle for backing strategic AI capacity on home soil. A bet on a different path to general intelligence Ineffable Intelligence was founded in 2025 by David Silver, the former Vice President of Reinforcement Learning at Google DeepMind and the principal architect of AlphaGo, AlphaZero and AlphaStar. He is joined by three further DeepMind alumni: Wojciech Czarnecki, Lasse Espeholt and Junhyuk Oh. All four have spent the past decade at the frontier of reinforcement learning research, the discipline behind some of the most consequential demonstrations of machine learning over the past ten years. The company describes its objective as building a “superlearner” — an AI system capable of acquiring knowledge directly from its own experience rather than from human-generated text or imagery. “Our mission is to make first contact with superintelligence,” Silver said in a statement accompanying the launch. “We are creating a superlearner that discovers all knowledge from its own experience, from elementary motor skills through to profound intellectual breakthroughs.” The framing is a deliberate departure from the dominant industry trajectory. Most leading AI laboratories, including OpenAI, Anthropic and Google DeepMind itself, have built large language models trained primarily on the corpus of the internet, then refined that training with human feedback. Ineffable’s wager is that the marginal returns on scaling text-based pretraining are diminishing and that the next leap in capability will come from agents that learn endlessly from the consequences of their own actions, in much the same way AlphaZero learnt the game of Go without studying any human matches. Why $1.1 billion at seed The size of the round is unusual even by the inflated standards of the 2026 AI capital cycle. Two factors appear to explain it. First, frontier reinforcement learning at the scale Ineffable describes is computationally extraordinarily expensive: the company will need to operate vast simulation environments and train very large models against them, an undertaking that consumes capital at a rate closer to physical R&D than to traditional software. Second, the round signals a strategic move by Europe’s investor and policy ecosystems to retain the most ambitious AI researchers on the continent. The presence of the UK Sovereign AI Fund alongside Sequoia, Lightspeed and Nvidia is the clearest expression of that intent. The British government has publicly framed the investment as a bet on breakthrough AI that “can discover new knowledge”, positioning the country as a willing co-investor in domestic frontier laboratories. For Ineffable, the implication is access not only to capital but to compute, regulatory engagement and the still-resilient academic talent base around UCL, Oxford, Cambridge and Imperial. Founder pledge of historic scale Alongside the funding announcement, Silver disclosed that he is committing 100 per cent of any personal proceeds from his Ineffable equity to charity via the Founders Pledge network — described by the organisation as the largest pledge in its history. At the round’s $5.1 billion valuation, that commitment could ultimately exceed several billion dollars if the company succeeds. It is a meaningful gesture in a sector where the reputational stakes around concentrated AI wealth are escalating, and one likely to be referenced in subsequent founder-led commitments. Implications for the European AI landscape Ineffable’s emergence reshapes the European AI map in three concrete ways. It establishes London as the home of the continent’s largest-ever seed-stage company, complicating Paris’s recent narrative of frontier-AI primacy after Mistral’s earlier rounds. It validates a thesis — that reinforcement learning, not transformer scaling, is the next frontier — that has lately been losing capital share to language-model incumbents. And it confirms that the UK government is now willing to act as a balance-sheet co-investor in domestic AI laboratories, a posture much closer to the French model than to the predominantly grant-based regimes elsewhere in Europe. The execution risk is non-trivial. Reinforcement learning at frontier scale has historically required years of careful environment design before producing competitive systems, and Ineffable’s “first contact” framing sets a high bar against which it will be judged. But for now, with a billion dollars on the balance sheet, four of the discipline’s most accomplished researchers in the founding team and a sovereign co-investor at its back, Ineffable Intelligence is the most heavily resourced new entrant in the European AI cycle. Sesamers covers European fundraising rounds across deeptech, fintech and AI. Source: tech.eu.

Fundraising 5 days ago

Belfast's Cloudsmith has raised $72M Series C led by TCV, with Insight Partners participating, to expand its artifact management platform and secure the AI-era software supply chain.

Fundraising 5 days ago

Berlin’s VREY has raised €3.3M seed led by Rubio Impact Ventures to roll out rooftop solar software for Germany’s multi-family buildings.

Subscribe to
our Newsletter!

Stay at the forefront with our curated guide to the best upcoming Tech events.