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AmphiStar Secures €2.5M SPRIND Biosurfactants Funding

Another win for Belgian biotech. AmphiStar has secured €2.5 million in fresh funding from SPRIND, Germany’s Federal Agency for Disruptive Innovation, marking the company’s third consecutive grant from the prestigious innovation program. This latest biosurfactants funding brings AmphiStar’s total SPRIND support to €6 million since 2023, underscoring growing confidence in the Ghent-based startup’s potential to disrupt the €60 billion global surfactants market.

The grant enables AmphiStar to advance to Stage 3 of SPRIND’s Circular Biomanufacturing Challenge, where five teams will compete to produce three different products from waste in 180 days of continuous production. AmphiStar previously achieved 75 days of continuous fermentation in Stage 1, exceeding SPRIND’s 60-day target and demonstrating the commercial viability of waste-based biosurfactant manufacturing at scale.

Accelerating Circular Biosurfactants Manufacturing

The funding accelerates AmphiStar’s industrialization of continuous fermentation technology for producing sustainable biosurfactants from upcycled bio-based waste feedstocks. Unlike conventional surfactants derived from fossil fuels or palm oil, AmphiStar’s microbial biosurfactants are produced through fermentation processes similar to brewing beer, using waste materials like supermarket food waste and agri-food side streams.

“This renewed SPRIND support demonstrates strong confidence in AmphiStar’s vision and technological potential,” said Dr. Sophie Roelants, COO and Co-Founder. “The funding will help us optimise our continuous fermentation process further and unlock the next phase of commercialisation, bringing truly sustainable, waste-based biosurfactants closer to mainstream markets.”

The company’s synthetic biology platform uses the yeast organism Starmerella bombicola to produce over 80 distinct biosurfactant molecules, each tailored for specific applications in personal care, home care, and industrial sectors. Recent Life Cycle Analysis confirms AmphiStar’s biosurfactants deliver fourfold lower global warming potential compared to non-upcycled alternatives.

European Leadership in Sustainable Chemistry

The SPRIND recognition comes as AmphiStar expands its commercial footprint across Europe and North America. The company recently partnered with Kensing in North America and Caldic in Europe to distribute its AmphiClean and AmphiCare product lines, marking key steps toward mainstream adoption of circular biosurfactants.

“It is an honor to be recognized as one of the final five participants in Stage 3 of the SPRIND Challenge, following the challenging and thorough assessment conducted by the expert jury,” said Pierre-Franck Valentin, CEO. “This funding strengthens our ability to deliver high-performance, circular ingredients that reduce environmental impact and accelerate the transition to a low-carbon, sustainable economy.”

AmphiStar has now raised over €24 million since its 2021 founding, including previous SPRIND grants (€1.5M in 2023, €2M in 2024), a €12.5M European Innovation Council investment, and backing from European Circular Bioeconomy Fund, Qbic, and PMV. The startup spun out from 15 years of research at Ghent University and aims to replace fossil-based surfactants in an industry producing 20 million tonnes annually.

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Fundraising 2 hours ago

London-based AI laboratory Ineffable Intelligence has emerged from stealth with a $1.1 billion seed round at a $5.1 billion post-money valuation, the company confirmed on 27 April 2026. The financing is the largest seed round ever raised by a European company and one of the largest first-money-in rounds in the global history of artificial intelligence. The round was co-led by Sequoia Capital and Lightspeed Venture Partners. Participating investors included Nvidia, DST Global, Index Ventures, Google, and the UK Sovereign AI Fund, the British government’s recently established vehicle for backing strategic AI capacity on home soil. A bet on a different path to general intelligence Ineffable Intelligence was founded in 2025 by David Silver, the former Vice President of Reinforcement Learning at Google DeepMind and the principal architect of AlphaGo, AlphaZero and AlphaStar. He is joined by three further DeepMind alumni: Wojciech Czarnecki, Lasse Espeholt and Junhyuk Oh. All four have spent the past decade at the frontier of reinforcement learning research, the discipline behind some of the most consequential demonstrations of machine learning over the past ten years. The company describes its objective as building a “superlearner” — an AI system capable of acquiring knowledge directly from its own experience rather than from human-generated text or imagery. “Our mission is to make first contact with superintelligence,” Silver said in a statement accompanying the launch. “We are creating a superlearner that discovers all knowledge from its own experience, from elementary motor skills through to profound intellectual breakthroughs.” The framing is a deliberate departure from the dominant industry trajectory. Most leading AI laboratories, including OpenAI, Anthropic and Google DeepMind itself, have built large language models trained primarily on the corpus of the internet, then refined that training with human feedback. Ineffable’s wager is that the marginal returns on scaling text-based pretraining are diminishing and that the next leap in capability will come from agents that learn endlessly from the consequences of their own actions, in much the same way AlphaZero learnt the game of Go without studying any human matches. Why $1.1 billion at seed The size of the round is unusual even by the inflated standards of the 2026 AI capital cycle. Two factors appear to explain it. First, frontier reinforcement learning at the scale Ineffable describes is computationally extraordinarily expensive: the company will need to operate vast simulation environments and train very large models against them, an undertaking that consumes capital at a rate closer to physical R&D than to traditional software. Second, the round signals a strategic move by Europe’s investor and policy ecosystems to retain the most ambitious AI researchers on the continent. The presence of the UK Sovereign AI Fund alongside Sequoia, Lightspeed and Nvidia is the clearest expression of that intent. The British government has publicly framed the investment as a bet on breakthrough AI that “can discover new knowledge”, positioning the country as a willing co-investor in domestic frontier laboratories. For Ineffable, the implication is access not only to capital but to compute, regulatory engagement and the still-resilient academic talent base around UCL, Oxford, Cambridge and Imperial. Founder pledge of historic scale Alongside the funding announcement, Silver disclosed that he is committing 100 per cent of any personal proceeds from his Ineffable equity to charity via the Founders Pledge network — described by the organisation as the largest pledge in its history. At the round’s $5.1 billion valuation, that commitment could ultimately exceed several billion dollars if the company succeeds. It is a meaningful gesture in a sector where the reputational stakes around concentrated AI wealth are escalating, and one likely to be referenced in subsequent founder-led commitments. Implications for the European AI landscape Ineffable’s emergence reshapes the European AI map in three concrete ways. It establishes London as the home of the continent’s largest-ever seed-stage company, complicating Paris’s recent narrative of frontier-AI primacy after Mistral’s earlier rounds. It validates a thesis — that reinforcement learning, not transformer scaling, is the next frontier — that has lately been losing capital share to language-model incumbents. And it confirms that the UK government is now willing to act as a balance-sheet co-investor in domestic AI laboratories, a posture much closer to the French model than to the predominantly grant-based regimes elsewhere in Europe. The execution risk is non-trivial. Reinforcement learning at frontier scale has historically required years of careful environment design before producing competitive systems, and Ineffable’s “first contact” framing sets a high bar against which it will be judged. But for now, with a billion dollars on the balance sheet, four of the discipline’s most accomplished researchers in the founding team and a sovereign co-investor at its back, Ineffable Intelligence is the most heavily resourced new entrant in the European AI cycle. Sesamers covers European fundraising rounds across deeptech, fintech and AI. Source: tech.eu.

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